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新的研究发现,当新冠状病毒感染细胞时,它不仅会损害细胞的活动,还会改变它们的功能。
研究人员发现,当胰腺中产生胰岛素的细胞被病毒感染时,它们不仅会导致胰腺细胞减少胰岛素分泌,还会致使其产生葡萄糖和消化酶,而实际上这并不是其应有的功能。“我们称之为细胞使命的改变,”这项研究的负责人Shuibing Chen博士说。周二,她在欧洲糖尿病研究协会(European Association for the study of Diabetes)的年度会议上发表的演讲,描述了这项研究工作。
早些时候,研究人员在《细胞代谢》(Cell Metabolism)杂志上的一篇报告中指出,目前还不清楚这种变化是持久的,还是可能是可逆的。Chen博士指出,一些COVID-19患者在感染后不久就患上了糖尿病。她在一份声明中说:“在这次COVID-19大流行中,肯定值得调查新发糖尿病患者的比例。”她的团队一直在对新冠状病毒进行实验和研究,这些细胞经过工程改造,可以制造类似肺、肝、肠、心脏和神经系统的微型器官或类器官。
Chen博士告诉路透社,他们的研究发现,细胞功能的丧失也可能发生在肺组织中。
POLARZONE编译自REUTERS的报道
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